Characterization of Tumor-Associated Macrophages and the Immune Microenvironment in Limited-Stage Neuroendocrine-High and -Low Small Cell Lung Cancer

Characterization of Tumor-Associated Macrophages and the Immune Microenvironment in Limited-Stage Neuroendocrine-High and -Low Small Cell Lung Cancer

This study aims to characterize tumor-infiltrating macrophages (TAMs), myeloid-derived suppressor cells (MDSC), and the related molecular milieu regulating anti-tumor immunity in limited-stage neuroendocrine (NE)-high and NE-low small cell lung cancer. Primary tumors and matched lymph node (LN) meta...

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Bibliographic Details
Main Authors: David Dora, Christopher Rivard, Hui Yu, Shivaun Lueke Pickard, Viktoria Laszlo, Tunde Harko, Zsolt Megyesfalvi, Elek Dinya, Csongor Gerdan, Gabor Szegvari, Fred R. Hirsch, Balazs Dome, Zoltan Lohinai
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biology
Subjects:
SCLC
neuroendocrine subtype
macrophage
tumor microenvironment
fGSEA
Online Access:https://www.mdpi.com/2079-7737/10/6/502

Internet

https://www.mdpi.com/2079-7737/10/6/502

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