Glycolaldehyde induces endoplasmic reticulum stress and apoptosis in Schwann cells

Schwann cell injury is caused by diabetic neuropathy. The apoptosis of Schwann cells plays a pivotal role in diabetic nerve dysfunction. Glycolaldehyde is a precursor of advanced glycation end products that contribute to the pathogenesis of diabetic neuropathy. In this study, we examined whether gly...

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Bibliographic Details
Main Authors: Keisuke Sato, Ryosuke Tatsunami, Kaori Yama, Yu Murao, Yoshiko Tampo
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750015300780