Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2

Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2

Truncated oxidized glycerophospholipids (ox-PLs) are bioactive lipids resulting from oxidative stress. The catabolic pathways for truncated ox-PLs are not fully understood. Lysosomal phospholipase A2 (LPLA2) with phospholipase A and transacylase activities is a key enzyme in phospholipid homeostasis...

Full description

Bibliographic Details
Main Authors: Akira Abe, Miki Hiraoka, Hiroshi Ohguro, John J. Tesmer, James A. Shayman
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Journal of Lipid Research
Subjects:
lysosome
truncated oxidized phospholipid
catabolic pathway
positional specificity
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314152

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520314152

Similar Items