Inositol 1, 4, 5-trisphosphate-dependent nuclear calcium signals regulate angiogenesis and cell motility in triple negative breast cancer.

Increases in nuclear calcium concentration generate specific biological outcomes that differ from those resulting from increased cytoplasmic calcium. Nuclear calcium effects on tumor cell proliferation are widely appreciated; nevertheless, its involvement in other steps of tumor progression is not w...

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Main Authors: Erika Guimarães, Rodrigo Machado, Matheus de Castro Fonseca, Andressa França, Clarissa Carvalho, Ana Cândida Araújo E Silva, Brígida Almeida, Puebla Cassini, Bárbara Hissa, Luciana Drumond, Carlos Gonçalves, Gabriel Fernandes, Marina De Brot, Márcio Moraes, Lucíola Barcelos, José Miguel Ortega, André Oliveira, M Fátima Leite
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5380351?pdf=render