Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin.

Receptor-type protein tyrosine phosphatases (RPTPs) of the R3 subgroup play key roles in the immune, vascular and nervous systems. They are characterised by a large ectodomain comprising multiple FNIII-like repeats, a transmembrane domain, and a single intracellular phosphatase domain. The functiona...

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Bibliographic Details
Main Authors: Olga Dorofejeva, Alastair J Barr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5604967?pdf=render