αA-crystallin R49C<sup>neo </sup>mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice
<p>Abstract</p> <p>Background</p> <p>αA-crystallin (CRYAA/HSPB4), a major component of all vertebrate eye lenses, is a small heat shock protein responsible for maintaining lens transparency. The R49C mutation in the αA-crystallin protein is linked with non-syndromic, he...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-07-01
|
| Series: | BMC Ophthalmology |
| Online Access: | http://www.biomedcentral.com/1471-2415/9/4 |