Plasma biomarker analysis in pediatric ARDS: generating future framework from a pilot randomized control trial of methylprednisoloneA framework for identifying plasma biomarkers related to clinical outcomes in pediatric ARDS

Plasma biomarker analysis in pediatric ARDS: generating future framework from a pilot randomized control trial of methylprednisoloneA framework for identifying plasma biomarkers related to clinical outcomes in pediatric ARDS

Objective: Lung injury activates multiple pro-inflammatory pathways, including neutrophils, epithelial and endothelial injury, and coagulation factors leading to acute respiratory distress syndrome (ARDS). Low-dose methylprednisolone therapy (MPT) improved oxygenation and ventilation in early pedia...

Full description

Bibliographic Details
Main Authors: Dai eKimura, Jordy eSaravia, Cynthia R Rovnaghi, Gianfranco Umberto Meduri, Andreas eSchwingshackl, Stephania eCormier, Kanwaljeet J. S. Anand
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Pediatrics
Subjects:
Lung Injury
Methylprednisolone
Steroids
biomarker
ICAM-1
pediatric
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2016.00031/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fped.2016.00031/full

Similar Items