The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

Objective: Insulin resistance is associated with impaired receptor dependent hepatic uptake of triglyceride-rich lipoproteins (TRL), promoting hypertriglyceridemia and atherosclerosis. Next to low-density lipoprotein (LDL) receptor (LDLR) and syndecan-1, the LDLR-related protein 1 (LRP1) stimulated...

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Bibliographic Details
Main Authors: Alexander W. Fischer, Kirstin Albers, Lucia M. Krott, Britta Hoffzimmer, Markus Heine, Hartwig Schmale, Ludger Scheja, Philip L.S.M. Gordts, Joerg Heeren
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781830694X

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http://www.sciencedirect.com/science/article/pii/S221287781830694X

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