The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins
Objective: Insulin resistance is associated with impaired receptor dependent hepatic uptake of triglyceride-rich lipoproteins (TRL), promoting hypertriglyceridemia and atherosclerosis. Next to low-density lipoprotein (LDL) receptor (LDLR) and syndecan-1, the LDLR-related protein 1 (LRP1) stimulated...
Main Authors: | Alexander W. Fischer, Kirstin Albers, Lucia M. Krott, Britta Hoffzimmer, Markus Heine, Hartwig Schmale, Ludger Scheja, Philip L.S.M. Gordts, Joerg Heeren |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221287781830694X |
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