tRNA-derived fragments tRFGlnCTG induced by arterial injury promote vascular smooth muscle cell proliferation

tRNA-derived fragments tRFGlnCTG induced by arterial injury promote vascular smooth muscle cell proliferation

tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs) are originated from the specific cleavage of endogenous tRNAs or their precursors and regulate gene expression when the cells are in stressful circumstances. Here, we replicated the rat common carotid artery (CCA) intimal hyperplasia model and i...

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Bibliographic Details
Main Authors: Xiao-Ling Zhu, Tao Li, Yu Cao, Qing-Ping Yao, Xing Liu, Ying Li, Yang-Yang Guan, Ji-Jun Deng, Rui Jiang, Jun Jiang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
tRNA-derived fragments
intimal hyperplasia
vascular smooth muscle cell
proliferation
FAS receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303917

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http://www.sciencedirect.com/science/article/pii/S2162253120303917

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