Gencore: an efficient tool to generate consensus reads for error suppressing and duplicate removing of NGS data

Gencore: an efficient tool to generate consensus reads for error suppressing and duplicate removing of NGS data

Abstract Background Removing duplicates might be considered as a well-resolved problem in next-generation sequencing (NGS) data processing domain. However, as NGS technology gains more recognition in clinical application, researchers start to pay more attention to its sequencing errors, and prefer t...

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Bibliographic Details
Main Authors: Shifu Chen, Yanqing Zhou, Yaru Chen, Tanxiao Huang, Wenting Liao, Yun Xu, Zhicheng Li, Jia Gu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Next-generation sequencing
Unique molecular identifier
Consensus reads
Deduplication
Online Access:https://doi.org/10.1186/s12859-019-3280-9

Internet

https://doi.org/10.1186/s12859-019-3280-9

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