Transgenic mouse model harboring the transcriptional fusion ccl20-luciferase as a novel reporter of pro-inflammatory response.

Transgenic mouse model harboring the transcriptional fusion ccl20-luciferase as a novel reporter of pro-inflammatory response.

The chemokine CCL20, the unique ligand of CCR6 functions as an attractant of immune cells. Expression of CCL20 is induced by Toll-like Receptor (TLR) signaling or proinflammatory cytokine stimulation. However CCL20 is also constitutively produced at specific epithelial sites of mucosa. This expressi...

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Bibliographic Details
Main Authors: Martina Crispo, Laurye Van Maele, Julien Tabareau, Delphine Cayet, Agustina Errea, Ana María Ferreira, Martin Rumbo, Jean Claude Sirard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24265691/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24265691/?tool=EBI

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