Phenotypic and genetic evaluation of human monocyte-derived dendritic cells generated from whole blood for immunotherapy

Abstract Background Dendritic cells (DCs) recognize different pathogens and cancer cells and activate the adaptive immune response. The generation of effective DC-based cancer vaccines depends on the appropriate differentiation of monocytes in vitro. This study aimed to standardize a protocol for th...

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Bibliographic Details
Main Authors: Yousri M. Hussein, Doaa M. Hendawy, Abdalrahman N. Alghamdy, Nermin Raafat
Format: Article
Language:English
Published: SpringerOpen 2021-05-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Online Access:https://doi.org/10.1186/s43042-021-00168-7