Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6

Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6

Abstract Background Histone deacetylases (HDACs) are involved in epigenetic gene regulation via deacetylation of acetylated lysine residues of both histone and non-histone proteins. Among the 18 HDACs identified in humans, HDAC8, a class I HDAC, is best understood structurally and enzymatically. How...

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Bibliographic Details
Main Authors: G. R. Vanaja, Hemalatha Golaconda Ramulu, Arunasree M. Kalle
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Cell Communication and Signaling
Subjects:
HDAC8
Alpha tubulin
Tubulin deacetylase
HDAC6
Cervical cancer
Online Access:http://link.springer.com/article/10.1186/s12964-018-0231-4

Internet

http://link.springer.com/article/10.1186/s12964-018-0231-4

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