An Epistatic Interaction between <i>Pnpla2</i> and <i>Lipe</i> Reveals New Pathways of Adipose Tissue Lipolysis

An Epistatic Interaction between <i>Pnpla2</i> and <i>Lipe</i> Reveals New Pathways of Adipose Tissue Lipolysis

White adipose tissue (WAT) lipolysis contributes to energy balance during fasting. Lipolysis can proceed by the sequential hydrolysis of triglycerides (TGs) by adipose triglyceride lipase (ATGL), then of diacylglycerols (DGs) by hormone-sensitive lipase (HSL). We showed that the combined genetic def...

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Bibliographic Details
Main Authors: Xiao Zhang, Cong Cong Zhang, Hao Yang, Krishnakant G. Soni, Shu Pei Wang, Grant A. Mitchell, Jiang Wei Wu
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
transacylation
triglycerides/diacylglycerol
enzymology/enzyme mechanisms
lipolysis and fatty acid metabolism
lipids
obesity
Online Access:https://www.mdpi.com/2073-4409/8/5/395

Internet

https://www.mdpi.com/2073-4409/8/5/395

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