Chronic Stress Induces Structural Alterations in Splenic Lymphoid Tissue That Are Associated with Changes in Corticosterone Levels in Wistar-Kyoto Rats

Major depressive disorder patients present chronic stress and decreased immunity. The Wistar-Kyoto rat (WKY) is a strain in which the hypothalamic-pituitary-adrenal axis is overactivated. To determine whether chronic stress induces changes in corticosterone levels and splenic lymphoid tissue, 9-week...

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Bibliographic Details
Main Authors: María Eugenia Hernandez, Lucia Martinez-Mota, Citlaltepetl Salinas, Ricardo Marquez-Velasco, Nancy G. Hernandez-Chan, Jorge Morales-Montor, Mayra Pérez-Tapia, María L. Streber, Ivonne Granados-Camacho, Enrique Becerril, Baquera-Heredia Javier, Lenin Pavón
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/868742