Phosphate-Linked Silibinin Dimers (PLSd): New Promising Modified Metabolites

Phosphate-Linked Silibinin Dimers (PLSd): New Promising Modified Metabolites

By exploiting the regioselective protection of the hydroxyl groups of silibinin along with the well-known phosphoramidite chemistry, we have developed an efficient strategy for the synthesis of new silibinin-modified species, which we have named Phosphate-Linked Silibinin Dimers (PLSd), in which the...

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Bibliographic Details
Main Authors: Valeria Romanucci, Raffaele Gravante, Martina Cimafonte, Cinzia Di Marino, Gilles Mailhot, Marcello Brigante, Armando Zarrelli, Giovanni Di Fabio
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molecules
Subjects:
silibinin
phosphodiester
oligoflavonoids
xanthine/xanthine oxidase assay
radical scavengers
reactive oxygen species (ROS)
Online Access:https://www.mdpi.com/1420-3049/22/8/1323

Internet

https://www.mdpi.com/1420-3049/22/8/1323

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