IgG3+ B cells are associated with the development of multiple sclerosis

IgG3+ B cells are associated with the development of multiple sclerosis

Abstract Objectives Disease‐modifying therapies (DMTs) targeting B cells are amongst the most effective for preventing multiple sclerosis (MS) progression. IgG3 antibodies and their uncharacterised B‐cell clones are predicted to play a pathogenic role in MS. Identifying subsets of IgG3+ B cells invo...

Full description

Bibliographic Details
Main Authors: Felix Marsh‐Wakefield, Thomas Ashhurst, Stephanie Trend, Helen M McGuire, Pierre Juillard, Anna Zinger, Anderson P Jones, Allan G Kermode, Simon Hawke, Georges E Grau, Prue H Hart, Scott N Byrne
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
B cells
clinically isolated syndrome
mass cytometry
multiple sclerosis
phototherapy
Online Access:https://doi.org/10.1002/cti2.1133

Internet

https://doi.org/10.1002/cti2.1133

Similar Items