B-1a cells protect mice from sepsis-induced acute lung injury

B-1a cells protect mice from sepsis-induced acute lung injury

Abstract Background Sepsis morbidity and mortality are aggravated by acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Mouse B-1a cells are a phenotypically and functionally unique sub-population of B cells, providing immediate protection against infection by releasing natural a...

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Bibliographic Details
Main Authors: Monowar Aziz, Yasumasa Ode, Mian Zhou, Mahendar Ochani, Nichol E. Holodick, Thomas L. Rothstein, Ping Wang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Molecular Medicine
Subjects:
B-1a cells
Sepsis
Acute lung injury
Inflammation
Neutrophils
IL-10
Online Access:http://link.springer.com/article/10.1186/s10020-018-0029-2

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http://link.springer.com/article/10.1186/s10020-018-0029-2

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