Loss of <it>Dictyostelium </it>HSPC300 causes a <it>scar</it>-like phenotype and loss of SCAR protein

<p>Abstract</p> <p>Background</p> <p>SCAR/WAVE proteins couple signalling to actin polymerization, and are thus fundamental to the formation of pseudopods and lamellipods. They are controlled as part of a five-membered complex that includes the tiny HSPC300 protein. It...

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Bibliographic Details
Main Authors: Pollitt Alice Y, Insall Robert H
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/10/13