Adaptive NKG2C+CD57+ Natural Killer Cell and Tim-3 Expression During Viral Infections

Adaptive NKG2C+CD57+ Natural Killer Cell and Tim-3 Expression During Viral Infections

Repetitive stimulation by persistent pathogens such as human cytomegalovirus (HCMV) or human immunodeficiency virus (HIV) induces the differentiation of natural killer (NK) cells. This maturation pathway is characterized by the acquisition of phenotypic markers, CD2, CD57, and NKG2C, and effector fu...

Full description

Bibliographic Details
Main Authors: Hassen Kared, Serena Martelli, Shu Wen Tan, Yannick Simoni, Meng Li Chong, Siew Hwei Yap, Evan W. Newell, Sylvia L. F. Pender, Adeeba Kamarulzaman, Reena Rajasuriar, Anis Larbi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
maturation
exhaustion
senescence
checkpoint blockade
aging
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00686/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00686/full

Similar Items