Immune characteristics study of AG490, a signal pathway inhibitor, in EAE model mice
Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination, axonal damage and progressive neurologic dysfunction in central nervous system (CNS). Many evidences show that B cells play an important role in the pathogenesis of MS. Follicular helper T cells (Tfh) secrete IL-21 to p...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-02-01
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Series: | Saudi Journal of Biological Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X16300961 |