Hypothesis testing and power calculations for taxonomic-based human microbiome data.

Hypothesis testing and power calculations for taxonomic-based human microbiome data.

This paper presents new biostatistical methods for the analysis of microbiome data based on a fully parametric approach using all the data. The Dirichlet-multinomial distribution allows the analyst to calculate power and sample sizes for experimental design, perform tests of hypotheses (e.g., compar...

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Bibliographic Details
Main Authors: Patricio S La Rosa, J Paul Brooks, Elena Deych, Edward L Boone, David J Edwards, Qin Wang, Erica Sodergren, George Weinstock, William D Shannon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527355?pdf=render

Internet

http://europepmc.org/articles/PMC3527355?pdf=render

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