Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing <i>Escherichia coli</i> (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice

Shiga toxin (Stx)-producing <i>Escherichia coli</i> (STEC) strain B2F1 produces Stx type 2d, a toxin that becomes more toxic towards Vero cells in the presence of intestinal mucus. STEC that make Stx2d are more pathogenic to streptomycin (Str)-treated mice than most STEC that produce Stx...

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Bibliographic Details
Main Authors: Beth A. McNichol, Rebecca A. Bova, Kieron Torres, Lan N. Preston, Angela R. Melton-Celsa
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/1/64