Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice.

Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice.

Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. Toll-like receptors (TLRs) are signaling receptors in the innate immune system, although emerging evidence indicates their role in brain injury. We have therefore investi...

Full description

Bibliographic Details
Main Authors: Akbar Ahmad, Rosalia Crupi, Michela Campolo, Tiziana Genovese, Emanuela Esposito, Salvatore Cuzzocrea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3610903?pdf=render

Internet

http://europepmc.org/articles/PMC3610903?pdf=render

Similar Items