Regulatory Network Analysis of Mutated Genes Based on Multi-Omics Data Reveals the Exclusive Features in Tumor Immune Microenvironment Between Left-Sided and Right-Sided Colon Cancer

Regulatory Network Analysis of Mutated Genes Based on Multi-Omics Data Reveals the Exclusive Features in Tumor Immune Microenvironment Between Left-Sided and Right-Sided Colon Cancer

Left-sided colon cancer (LCC) and right-sided colon cancer (RCC) have distinct characteristics in tumor immune microenvironment (TIME). Although existing studies have shown a strong association between gene mutations and TIME, whether the regulatory mechanisms between gene mutations and TIME are dif...

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Bibliographic Details
Main Authors: Tianfei Yi, Yuwei Zhang, Derry Minyao Ng, Yang Xi, Meng Ye, Lvjun Cen, Jianjiong Li, Xiaoxiang Fan, Yanguo Li, Shiyun Hu, Hao Rong, Yangyang Xie, Guofang Zhao, Leyi Chen, Chen Chen, Shujing Ni, Jiaying Mi, Xiaoyu Dai, Qi Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
left-sided colon cancer (LCC)
right-sided colon cancer (RCC)
tumor immune microenvironment (TIME)
gene mutation
multi-omics
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.685515/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.685515/full

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