Diverse proteins aggregate in mild cognitive impairment and Alzheimer’s disease brain

Diverse proteins aggregate in mild cognitive impairment and Alzheimer’s disease brain

Abstract Background All cells accumulate insoluble protein aggregates throughout their lifespan. While many studies have characterized the canonical disease-associated protein aggregates, such as those associated with amyloid plaques, additional, undefined proteins aggregate in the brain and may be...

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Bibliographic Details
Main Authors: Devin Kepchia, Ling Huang, Richard Dargusch, Robert A. Rissman, Maxim N. Shokhirev, Wolfgang Fischer, David Schubert
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
Dementia
Insoluble protein
Secondary modifications
Proteomics
Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s13195-020-00641-2

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http://link.springer.com/article/10.1186/s13195-020-00641-2

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