Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth

Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth

Abstract Background Personalized cancer vaccines based on neoantigens have reached the clinical trial stage in melanoma. Different vaccination protocols showed efficacy in preclinical models without a clear indication of the quality and the number of neoantigens required for an effective cancer vacc...

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Bibliographic Details
Main Authors: Luigi Aurisicchio, Erika Salvatori, Lucia Lione, Silvio Bandini, Matteo Pallocca, Roberta Maggio, Maurizio Fanciulli, Francesca De Nicola, Frauke Goeman, Gennaro Ciliberto, Antonella Conforti, Laura Luberto, Fabio Palombo
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Immunotherapy
T cells
Affinity
Cancer vaccine
Neoantigen
Vaccination
Online Access:http://link.springer.com/article/10.1186/s13046-019-1084-4

Internet

http://link.springer.com/article/10.1186/s13046-019-1084-4

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