Comprehensive gene-based association study of a chromosome 20 linked region implicates novel risk loci for depressive symptoms in psychotic illness.

Prior genomewide scans of schizophrenia support evidence of linkage to regions of chromosome 20. However, association analyses have yet to provide support for any etiologically relevant variants.We analyzed 2988 LD-tagging single nucleotide polymorphisms (SNPs) in 327 genes on chromosome 20, to test...

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Bibliographic Details
Main Authors: T Bernard Bigdeli, Brion S Maher, Zhongming Zhao, Edwin J C G van den Oord, Dawn L Thiselton, Jingchun Sun, Bradley T Webb, Richard L Amdur, Brandon Wormley, Francis A O'Neill, Dermot Walsh, Brien P Riley, Kenneth S Kendler, Ayman H Fanous
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3248394?pdf=render