Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase

Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase

Cell–matrix adhesion and cell migration are physiologically important processes that also play a major role in cancer spreading. In cultured cells, matrix adhesion depends on integrin-containing contacts such as focal adhesions. Flotillin-1 and flotillin-2 are frequently overexpressed in cancers and...

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Bibliographic Details
Main Authors: Antje Banning, Tanja Babuke, Nina Kurrle, Melanie Meister, Mika O. Ruonala, Ritva Tikkanen
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Cells
Subjects:
focal adhesion
cancer
metastasis
cell migration
Online Access:http://www.mdpi.com/2073-4409/7/4/28

Internet

http://www.mdpi.com/2073-4409/7/4/28

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