Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage

<p>Abstract</p> <p>Background</p> <p>HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-receptors, which interact primarily with the third hypervariable loop (V3...

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Bibliographic Details
Main Authors: Vaisman Iosif I, Masso Majid
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/494