Estratégia de simplificação molecular no planejamento racional de fármacos: a descoberta de novo agente cardioativo Strategy of molecular simplification in rational drug design: the discovery of a new cardioactive agent
<abstract language="eng">In this article are described examples of the successful use of molecular simplification strategy in the discovery of new drugs from bioactive natural products and synthetic compounds. The discovery of a new cardiotonic derivative (37, 2-thienylidene-3,4-meth...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2002-12-01
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| Series: | Química Nova |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000700018 |