Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.

Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.

BACKGROUND: While protease-activated-receptor 1 (PAR(1)) plays a central role in tumor progression, little is known about the cell signaling involved. METHODOLOGY/PRINCIPAL FINDINGS: We show here the impact of PAR(1) cellular activities using both an orthotopic mouse mammary xenograft and a colorect...

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Bibliographic Details
Main Authors: Irit Cohen, Myriam Maoz, Hagit Turm, Sorina Grisaru-Granovsky, Bella Maly, Beatrice Uziely, Einat Weiss, Rinat Abramovitch, Eithan Gross, Oded Barzilay, Yun Qiu, Rachel Bar-Shavit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2886121?pdf=render

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http://europepmc.org/articles/PMC2886121?pdf=render

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