Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model.

Developing effective therapies for back pain associated with intervertebral disc (IVD) degeneration is a research priority since it is a major socioeconomic burden and current conservative and surgical treatments have limited success. Polyphenols are naturally occurring compounds in plant-derived fo...

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Bibliographic Details
Main Authors: Alon Lai, Lap Ho, Thomas W Evashwick-Rogler, Hironobu Watanabe, Jonathan Salandra, Beth A Winkelstein, Damien Laudier, Andrew C Hecht, Giulio M Pasinetti, James C Iatridis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223435