The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: a randomized controlled phase I trial.

The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: a randomized controlled phase I trial.

BACKGROUND:Fully efficient vaccines against malaria pre-erythrocytic stage are still lacking. The objective of this dose/adjuvant-finding study was to evaluate the safety, reactogenicity and immunogenicity of a vaccine candidate based on a peptide spanning the C-terminal region of Plasmodium falcipa...

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Bibliographic Details
Main Authors: Régine Audran, Floriana Lurati-Ruiz, Blaise Genton, Hildur E Blythman, Opokua Ofori-Anyinam, Christophe Reymond, Giampietro Corradin, François Spertini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2749339?pdf=render

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http://europepmc.org/articles/PMC2749339?pdf=render

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