T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis.

T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis.

BACKGROUND: Due to recent studies indicating that the deregulation of microRNAs (miRNAs) in T cells contributes to increased severity of rheumatoid arthritis, we hypothesized that deregulated miRNAs may interact with key mRNA targets controlling the function or differentiation of these cells in this...

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Bibliographic Details
Main Authors: Paula B Donate, Thais A Fornari, Claudia Macedo, Thiago M Cunha, Daniele C B Nascimento, Elza T Sakamoto-Hojo, Eduardo A Donadi, Fernando Q Cunha, Geraldo A Passos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554629?pdf=render

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http://europepmc.org/articles/PMC3554629?pdf=render

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