In Vitro Large Scale Production of Human Mature Red Blood Cells from Hematopoietic Stem Cells by Coculturing with Human Fetal Liver Stromal Cells

In vitro models of human erythropoiesis are useful in studying the mechanisms of erythroid differentiation in normal and pathological conditions. Here we describe an erythroid liquid culture system starting from cord blood derived hematopoietic stem cells (HSCs). HSCs were cultured for more than 50...

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Bibliographic Details
Main Authors: Jiafei Xi, Yanhua Li, Ruoyong Wang, Yunfang Wang, Xue Nan, Lijuan He, Peng Zhang, Lin Chen, Wen Yue, Xuetao Pei
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/807863