Anoctamin1 Induces Hyperproliferation of HaCaT Keratinocytes and Triggers Imiquimod-Induced Psoriasis-Like Skin Injury in Mice

Anoctamin1 Induces Hyperproliferation of HaCaT Keratinocytes and Triggers Imiquimod-Induced Psoriasis-Like Skin Injury in Mice

Psoriasis, a long-lasting and multifactorial skin disease, is related to comorbidities such as metabolic disease, depression, and psoriatic arthritis. Psoriasis occurs due to a variety of factors including keratinocyte hyperproliferation, inflammation, and abnormal differentiation. Proinflammatory c...

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Bibliographic Details
Main Authors: Mi Ran Choi, Hae Dong Kim, Sinyoung Cho, Seong Ho Jeon, Dong Hyun Kim, Jungwon Wee, Young Duk Yang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
anoctamin 1
ERK pathway
imiquimod
keratinocyte
psoriasis
Online Access:https://www.mdpi.com/1422-0067/22/13/7145

Internet

https://www.mdpi.com/1422-0067/22/13/7145

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