Selective constraint on noncoding regions of hominid genomes.

An important challenge for human evolutionary biology is to understand the genetic basis of human-chimpanzee differences. One influential idea holds that such differences depend, to a large extent, on adaptive changes in gene expression. An important step in assessing this hypothesis involves gainin...

Full description

Bibliographic Details
Main Authors: Eliot C Bush, Bruce T Lahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1314883?pdf=render