Gene expression profiling of loss of TET2 and/or JAK2V617F mutant hematopoietic stem cells from mouse models of myeloproliferative neoplasms

Gene expression profiling of loss of TET2 and/or JAK2V617F mutant hematopoietic stem cells from mouse models of myeloproliferative neoplasms

Myeloproliferative neoplasms (MPNs) are clinically characterized by the chronic overproduction of differentiated peripheral blood cells and the gradual expansion of malignant intramedullary/extramedullary hematopoiesis. In MPNs mutations in JAK2 MPL or CALR are detected mutually exclusive in more th...

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Bibliographic Details
Main Authors: Takuro Kameda, Kotaro Shide, Takumi Yamaji, Ayako Kamiunten, Masaaki Sekine, Tomonori Hidaka, Yoko Kubuki, Goro Sashida, Kazumasa Aoyama, Makoto Yoshimitsu, Hiroo Abe, Tadashi Miike, Hisayoshi Iwakiri, Yoshihiro Tahara, Shojiro Yamamoto, Satoru Hasuike, Kenji Nagata, Atsushi Iwama, Akira Kitanaka, Kazuya Shimoda
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Genomics Data
Subjects:
Microarray profiling
Loss of TET2
JAK2V617F
Hematopoietic stem cell
Myeloproliferative neoplasm
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015000367

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http://www.sciencedirect.com/science/article/pii/S2213596015000367

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