PPARγ Inhibits VSMC Proliferation and Migration via Attenuating Oxidative Stress through Upregulating UCP2.

Increasing evidence showed that abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) are common event in the pathophysiology of many vascular diseases, including atherosclerosis and restenosis after angioplasty. Among the underlying mechanisms, oxidative stress is one of the...

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Bibliographic Details
Main Authors: Yi Zhou, Ming-Jie Zhang, Bing-Hu Li, Lei Chen, Yan Pi, Yan-Wei Yin, Chun-Yan Long, Xu Wang, Meng-Jiao Sun, Xue Chen, Chang-Yue Gao, Jing-Cheng Li, Li-Li Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4856345?pdf=render