p53-Sensitive Epileptic Behavior and Inflammation in Ft1 Hypomorphic Mice

p53-Sensitive Epileptic Behavior and Inflammation in Ft1 Hypomorphic Mice

Epilepsy is a complex clinical condition characterized by repeated spontaneous seizures. Seizures have been linked to multiple drivers including DNA damage accumulation. Investigation of epilepsy physiopathology in humans imposes ethical and practical limitations, for this reason model systems are m...

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Bibliographic Details
Main Authors: Romina Burla, Mattia La Torre, Giorgia Zanetti, Alex Bastianelli, Chiara Merigliano, Simona Del Giudice, Alessandro Vercelli, Ferdinando Di Cunto, Marina Boido, Fiammetta Vernì, Isabella Saggio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
aging
epilepsy
DNA damage
p53
DNA repair
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00581/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00581/full

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