The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

<p><b>Abstract</b></p> <p><b>Background</b></p> <p>Prion diseases are neurodegenerative disorders characterized by the accumulation of an abnormal disease-associated prion protein, PrP<sup>Sc</sup>. In prion-infected brains, activated...

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Bibliographic Details
Main Authors: Shi Fushan, Yang Lifeng, Kouadir Mohammed, Yang Yang, Wang Jihong, Zhou Xiangmei, Yin Xiaomin, Zhao Deming
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Subjects:
Prion diseases
PrP106-126
NALP3 Inflammasome
IL-1β
Microglia
Online Access:http://www.jneuroinflammation.com/content/9/1/73

Internet

http://www.jneuroinflammation.com/content/9/1/73

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