Epidermal growth factor protects squamous cell carcinoma against cisplatin-induced cytotoxicity through increased interleukin-1β expression.

The expression of cytokines, such as IL-1β, and the activation of the epidermal growth factor receptor (EGFR) are crucial regulators in the process of carcinogenesis. The correlation between growth factor and activated cytokine signals in the control of tumor development is a critical issue to be cl...

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Bibliographic Details
Main Authors: Shian-Chin Ko, Chi-Ruei Huang, Jiunn-Min Shieh, Jhen-Hong Yang, Wen-Chang Chang, Ben-Kuen Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3562190?pdf=render