Tributylphosphane-promoted [3 + 2] annulation of 3-hydroxyoxindoles with acrylates: Synthesis of spirocyclic oxindole-lactones

The tributylphosphane-promoted [3 + 2] annulation reactions of 3-hydroxyoxindoles with acrylates have been developed to give a variety of pharmaceutically attractive spirocyclic oxindole-lactone derivatives in good to excellent yields. The structures of all the compounds were confirmed by 1H NMR, 13...

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Bibliographic Details
Main Authors: Qiaomei Jin, Jian Zhang, Shihe Hu
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610317300716