Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma

Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma

Background: CD38 is involved in the adenosine pathway, which represents one of the immunosuppressive mechanisms in cancer. CD38 is broadly expressed across immune cell subsets, including human macrophages differentiated in vitro from monocytes, but expression by tissue-resident macrophages remains t...

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Bibliographic Details
Main Authors: Jian Hang Lam, Harry Ho Man Ng, Chun Jye Lim, Xin Ni Sim, Fabio Malavasi, Huihua Li, Josh Jie Hua Loh, Khin Sabai, Joo-Kyung Kim, Clara Chong Hui Ong, Tracy Loh, Wei Qiang Leow, Su Pin Choo, Han Chong Toh, Ser Yee Lee, Chung Yip Chan, Valerie Chew, Tong Seng Lim, Joe Yeong, Tony Kiat Hon Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
macrophage
CD38
marker
prognosis
cancer
hepatocellular carcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02093/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02093/full

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