DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression

DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression

Cell contact inhibition (CCI) is deregulated in cancer. Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. We found that dual-specificity phosphatase 10 (DUSP10) is involved in CRC. DUSP10 overexpression increased the growth of CRC cell lines and mouse xenografts, while t...

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Bibliographic Details
Main Authors: Marta Jiménez-Martínez, Cristina M. Ostalé, Lennart R. van der Burg, Javier Galán-Martínez, James C. H. Hardwick, Ricardo López-Pérez, Lukas J. A. C. Hawinkels, Konstantinos Stamatakis, Manuel Fresno
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
protein
cancer
cell contact inhibition
cell proliferation
prognosis
Online Access:https://www.mdpi.com/2072-6694/11/11/1767

Internet

https://www.mdpi.com/2072-6694/11/11/1767

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