Lentiviral Vectors for T Cell Engineering: Clinical Applications, Bioprocessing and Future Perspectives

Lentiviral Vectors for T Cell Engineering: Clinical Applications, Bioprocessing and Future Perspectives

Lentiviral vectors have played a critical role in the emergence of gene-modified cell therapies, specifically T cell therapies. Tisagenlecleucel (Kymriah), axicabtagene ciloleucel (Yescarta) and most recently brexucabtagene autoleucel (Tecartus) are examples of T cell therapies which are now commerc...

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Bibliographic Details
Main Authors: Roman P. Labbé, Sandrine Vessillier, Qasim A. Rafiq
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
CAR
T cell
lentivirus
viral vector
bioprocessing
manufacture
Online Access:https://www.mdpi.com/1999-4915/13/8/1528

Internet

https://www.mdpi.com/1999-4915/13/8/1528

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