A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain

A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain

Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK. The purpose of this genome-wide association study (GWAS) was to identify genetic contributors to this disorder. Ca...

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Bibliographic Details
Main Authors: Weihua Meng, Harshal A. Deshmukh, Louise A. Donnelly, Nicola Torrance, Helen M. Colhoun, Colin N.A. Palmer, Blair H. Smith
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:EBioMedicine
Subjects:
Neuropathic pain
GWAS
Heritability
Sex-specific
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300955

Internet

http://www.sciencedirect.com/science/article/pii/S2352396415300955

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