The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses.

The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses.

Memory CD8 T cells provide protection to immune hosts by eliminating pathogen-infected cells during re-infection. While parameters influencing the generation of primary (1°) CD8 T cells are well established, the factors controlling the development of secondary (2°) CD8 T cell responses remain largel...

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Bibliographic Details
Main Authors: Shaniya H Khan, Matthew D Martin, Gabriel R Starbeck-Miller, Hai-Hui Xue, John T Harty, Vladimir P Badovinac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4592272?pdf=render

Internet

http://europepmc.org/articles/PMC4592272?pdf=render

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